October 10, 2018
October 10, 2018 —
Early adoption of tobacco control efforts in California led to fewer people ever smoking, reduced the amount used by those who do smoke and helped smokers quit at a younger age — when their risk of developing lung cancer is lowest. As a result, lung cancer deaths are 28 percent lower in California compared to the rest of the country and the gap is widening each year by almost a percentage point.
August 8, 2018
August 8, 2018 —
To understand why some patients with appendix cancer respond to standard treatment while others do not, University of California San Diego School of Medicine and Moores Cancer Center researchers, in collaboration with Foundation Medicine, performed genetic profiling on 703 appendiceal tumors — the largest such study of this disease to date — to compare mutations present in both cancer types.
July 25, 2018
July 25, 2018 —
In a study published online July 25 in the journal Nature, University of California San Diego School of Medicine researchers identified a signaling pathway that activates the NLRP3 inflammasome implicated in several severe chronic inflammatory disorders.
July 9, 2018
July 9, 2018 —
Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at the atomic level. This previously unreported biochemical interaction of curcumin leads to inhibition of DYRK2 that impairs cell proliferation and reduces cancer burden.
April 19, 2018
April 19, 2018 —
For Angela Valdez, being diagnosed with diabetes was an awakening. The disorder ran in her family, but she didn't think it would happen to her. And when it did, she acted by modifying her diet and physical activity. She was doing everything right - almost.
March 26, 2018
March 26, 2018 —
Receptivity to advertising for e-cigarettes, cigarettes and cigars were confirmed to be associated with those who would try the respective tobacco product within one year. However, receptivity to e-cigarette advertising also independently increased the odds that 12- to 21-year-olds who have never smoked would try cigarette smoking within the next year by 60 percent. This finding, publishing in the March 26 issue of JAMA Pediatrics, was independent of receptivity to cigarette advertising.
February 28, 2018
February 28, 2018 —
Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.
February 8, 2018
February 8, 2018 —
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a paper publishing in Cell on February 8, University of California San Diego School of Medicine researchers identify the enzyme TANK-binding kinase 1 (TBK1) as a key player in the control of energy expenditure during both obesity and fasting.
February 7, 2018
February 7, 2018 —
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.
January 11, 2018
January 11, 2018 —
UC San Diego Health and Eisenhower Health signed a five-year affiliation agreement to expand cancer services for residents of Coachella Valley. Starting in January 2018, as a member of the UC San Diego Health Cancer Network, patients of Eisenhower Health will have enhanced access to world-class cancer care, both at Eisenhower Lucy Curci Cancer Center and at UC San Diego Health.
